Article
CcpA mutants with differential activities in Bacillus subtilis.
Journal of molecular microbiology and biotechnology - 1 Jan 2007
Sprehe Mareen, Seidel Gerald, Diel Marco, Hillen Wolfgang
Abstract excerpt
CcpA is the master regulator for carbon catabolite regulation in Bacillus subtilis and regulates more than 300 genes by repression or activation. To revealthe effects of different functional domains of CcpA on various regulatory modes, we compared the activities of CcpA point mutants in activation (alsS, ackA) and repression (xynP, gntR). CcpA variants mutated at residues in the HPrSerP-binding region without...
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