Article
Identification of ligands affecting the activity of the transcriptional repressor CcpN from Bacillus subtilis.
Journal of molecular biology - 27 Jun 2008
Licht Andreas, Golbik Ralph, Brantl Sabine
Abstract excerpt
Carbon catabolite repression in Bacillus subtilis is mediated primarily by the major regulator CcpA. However, sugar-dependent repression of three genes, sr1 encoding a small nontranslated RNA and two genes coding for gluconeogenic enzymes, gapB and pckA, is carried out by the transcriptional repressor CcpN (control catabolite protein of gluconeogenic genes). It has previously been shown that ccpN is...
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