Article
Direct and indirect roles of CcpA in regulation of Bacillus subtilis Krebs cycle genes.
Molecular microbiology - 1 Jul 2002
Kim Hyun-Jin, Roux Agnes, Sonenshein Abraham L
Abstract excerpt
Carbon catabolite repression of the Bacillus subtilis citrate synthase (citZ) and aconitase (citB) genes, previously known to be regulated by CcpC, was shown to depend on CcpA as well. Transcription of the citZ gene was partially derepressed in ccpA and ccpC single mutants and fully derepressed in a ccpA ccpC double mutant. DNase I footprinting studies showed that CcpA binds to a catabolite-responsive element...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
