Article
The Bacillus subtilis catabolite control protein CcpA exerts all its regulatory functions by DNA-binding.
FEMS microbiology letters - 11 Sept 2001
Ludwig H, Stülke J
Abstract excerpt
In Bacillus subtilis, carbon catabolite control is mediated by the regulatory protein CcpA. In addition to loss of catabolite repression, ccpA mutants exhibit a severe growth defect. They are not able to grow with glucose and ammonium as single sources of carbon and nitrogen, respectively. Only ccpA mutant strains carrying either secondary suppressor mutations or that are affected in specific amino acids in the...
Topics
- Alleles
- Bacillus subtilis
- Bacterial Proteins
- Culture Media
- DNA, Bacterial
- DNA-Binding Proteins
- Gene Deletion
- Glucose
- Repressor Proteins
- Xylosidases
