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Article

Analysis of CcpA mutations defective in carbon catabolite repression in Bacillus megaterium.

FEMS microbiology letters - 1 Aug 1997

Kraus A, Hillen W

Abstract excerpt

Five mutations in ccpA of Bacillus megaterium with impaired functions were analysed for carbon catabolite repression. The phenotypes support the hypothesis that CcpA assumes a PurR/LacI fold. The completely inactive mutants CcpA119GE and CcpA326am cause alterations which are incompatible with that fold. A mutation with reduced activity, CcpA81GE, affects a site that would be partially surface exposed and may...

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Identifiers

PMID: 9252590
DOI: 10.1111/j.1574-6968.1997.tb10485.x

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