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Cancer Stem Cells: Targets and Potential Biomarkers for Radiotherapy

6 Oct 2011

Abstract excerpt

Cancer stem cells (CSC) have the unique ability to cause tumor recurrences if they survive treatment. Radiotherapy has curative potential because it has been functionally shown to sufficiently inactivate CSCs. It is well known that CSCs mediate the radiation resistance of tumors by tumor-specific factors, such as the pretreatment number of CSCs and repopulation or reoxygenation during fractionated radiotherapy....

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PMID: 21976536
DOI: 10.1158/1078-0432.ccr-10-2639

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