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Article

Essential roles for GSK-3s and GSK-3-primed substrates in neurotrophin-induced and hippocampal axon growth.

Neuron - 21 Dec 2006

Kim Woo-Yang, Zhou Feng-Quan, Zhou Jiang, Yokota Yukako, Wang Yan-Min, Yoshimura Takeshi, Kaibuchi Kozo, Woodgett James R, Anton E S, Snider William D

Abstract excerpt

Glycogen synthase kinase-3beta (GSK-3beta) is thought to mediate morphological responses to a variety of extracellular signals. Surprisingly, we found no gross morphological deficits in nervous system development in GSK-3beta null mice. We therefore designed an shRNA that targeted both GSK-3 isof...

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Identifiers

PMID: 17178402
DOI: 10.1016/j.neuron.2006.10.031
PMCID: PMC4167845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17178402-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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