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Article

Synthesis of enzymatically active human alpha-L-iduronidase in Arabidopsis cgl (complex glycan-deficient) seeds.

Plant biotechnology journal - 1 Mar 2006

Downing Willa L, Galpin Jason D, Clemens Sabine, Lauzon Shauna M, Samuels A Lacey, Pidkowich Mark S, Clarke Lorne A, Kermode Allison R

Abstract excerpt

As an initial step to develop plants as systems to produce enzymes for the treatment of lysosomal storage disorders, Arabidopsis thaliana wild-type (Col-0) plants were transformed with a construct to express human alpha-l-iduronidase (IDUA; EC 3.2.1.76) in seeds using the promoter and other regulatory sequences of the Phaseolus vulgaris arcelin 5-I gene. IDUA protein was easily detected on Western blots of...

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Source

Identifiers

PMID: 17177794
DOI: 10.1111/j.1467-7652.2005.00166.x

Genes

IDUA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Synthesis of enzymatically active human alpha-L-iduronidase in Arabidopsis cgl (complex glycan-deficient) seeds.PMID 17177794Read ↗

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