Association between a polymorphism in the promoter region of the TPH2 gene and the personality trait of harm avoidance.

doi:10.1017/S1461145706007073

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Article

Association between a polymorphism in the promoter region of the TPH2 gene and the personality trait of harm avoidance.

The international journal of neuropsychopharmacology - 1 Jun 2007

Reuter Martin, Kuepper Yvonne, Hennig Juergen

Abstract excerpt

In a genetic association study the role of the -703 G/T (rs4570625) polymorphism, located in the promoter region of the tryptophan hydroxylase 2 gene (TPH2), in personality traits was investigated in a sample of 404 healthy Caucasian subjects. A significant association between harm avoidance (HA), a trait related to anxiety, and the -703 G/T polymorphism was detected supporting the findings by Gutknecht and...

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Identifiers

PMID: 17176491
DOI: 10.1017/S1461145706007073

Genes

TPH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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