Article
Association study between the -1021C/T polymorphism of the dopamine-beta-hydroxylase gene promoter and personality traits in healthy subjects.
Neuroscience letters - 2 Oct 2009
Kamata Mitsuhiro, Suzuki Akihito, Matsumoto Yoshihiko, Shibuya Naoshi, Togashi Hitoshi, Goto Kaoru, Otani Koichi
Abstract excerpt
Dopamine and norepinephrine are implicated in the characterization of personality traits. Dopamine-beta-hydroxylase (DBH) is the enzyme responsible for conversion of dopamine to norepinephrine, and thus plays an important role in controlling dispositions of these neurotransmitters. Previous studies have shown that the -1021C/T polymorphism of the DBH gene promoter influences plasma DBH activity. Therefore, we...
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