Article
Mutational analysis of ABC proteins.
Archives of biochemistry and biophysics - 1 Aug 2008
Loo Tip W, Clarke David M
Abstract excerpt
The 49 human members of the ATP-binding cassette (ABC) family of proteins are involved in a wide range of activities such as active transport of compounds across membranes, extraction of compounds out of membranes, functioning as ion channels, or regulators of channel activity. Mutations and/or overexpression of many of the proteins can have adverse effects on health. A goal in the study of ABC proteins is to...
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