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Stem cells from umbilical cord blood differentiate into myotubes and express dystrophin <i>in vitro</i> only after exposure to <i>in vivo</i> muscle environment

20 Mar 2007

Abstract excerpt

BACKGROUND INFORMATION: Duchenne muscular dystrophy is a disease characterized by progressive and irreversible muscle degeneration for which there is no therapy. HUCB (human umbilical cord blood) has been considered as an important source of haematopoietic and mesenchymal stem cells, each having been shown to differentiate into distinct cell types. However, it remains unclear if these cells are able to...

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PMID: 17166095
DOI: 10.1042/bc20060075

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