Article
Lack of a skeletal muscle phenotype in adult human bone marrow stromal cells following xenogeneic-free expansion.
Stem cell research & therapy - 22 Feb 2020
Barisic Dominik, Erb Marita, Follo Marie, Al-Mudaris Dahlia, Rolauffs Bernd, Hart Melanie L
Abstract excerpt
BACKGROUND: Many studies have elegantly shown that murine and rat bone marrow-derived mesenchymal stromal cells (bmMSCs) contribute to muscle regeneration and improve muscle function. Yet, the ability of transplanted human bmMSCs to manifest myogenic potential shows conflicting results. While human adipose- and umbilical cord-derived MSCs can be differentiated into a skeletal muscle phenotype using horse serum...
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