Article
Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?
European journal of human genetics : EJHG - 1 Mar 2007
Bourgain Catherine, Génin Emmanuelle, Cox Nancy, Clerget-Darpoux Françoise
Abstract excerpt
With the availability of dense maps of anonymous and frequent SNPs spanning the whole human genome, genome-wide association studies are now becoming a reality. In this paper, we discuss the utility of these approaches to detect genetic risk variants involved in complex disease susceptibility and, in the best case scenario where a signal is detected, how helpful it will be to the understanding of the pathological...
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