Article
A new algorithm for deduction of hepatitis B surface antigen subtype determinants from the amino acid sequence.
Intervirology - 1 Jan 2007
Purdy Michael A, Talekar Ganesh, Swenson Paul, Araujo Aufra, Fields Howard
Abstract excerpt
OBJECTIVE: We have reexamined hepatitis B virus subtypes to determine the role of specific HBsAg amino acids in serologic reactivity because of problematic genotype/subtype associations seen in a set of geographically diverse serum specimens. METHODS: We obtained DNA sequences for 491 HBsAg-positive specimens from geographically distinct locations, determined their genotypes through phylogenetic analysis, and...
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