Article
HBV core sequence: definition of genotype-specific variability and correlation with geographical origin.
Journal of viral hepatitis - 1 Nov 2004
Jazayeri S M, Jazayeri M, Basuni A A, Sran N, Gish R, Cooksley G, Locarnini S, Carman W F
Abstract excerpt
There are eight genotypes and nine subtypes of HBV. Small differences in geographical origin are associated with sequence changes in the surface gene. Here, we compared core gene sequences from different genotypes and geographical regions. Specific combinations of 24 amino acid substitutions at nine residues allowed allocation of a sequence to a subtype. Six of these nine residues were located in different T cell...
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