Article
Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients.
Transplantation - 27 Jul 2011
Myhre Hans-Arne, Haug Dorenberg Dagny, Kristiansen Knut Ivan, Rollag Halvor, Leivestad Torbjørn, Asberg Anders, Hartmann Anders
Abstract excerpt
BACKGROUND: Cytomegalovirus (CMV) infections in kidney transplant recipients are in most cases successfully treated with oral valganciclovir (VGCV). However, in a few percent of patients, mutations in the UL 97 or UL 54 gene lead to drug resistance. METHODS: We investigated the incidence and outcomes of ganciclovir-resistant CMV viremia in all 1244 kidney recipients transplanted at our center from 2004 through...
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