Article
[Evaluation of the influence of GSTT1 and GSTM1 null genotypes in head and neck carcinogenesis].
Revista da Associacao Medica Brasileira (1992) - 1 Jan 2000
Goloni-Bertollo Eny Maria, Biselli Joice Matos, Corrêa Léa Carolina Delima, Maníglia José Victor, Rossit Andréa Regina Baptista, Ruiz Mariângela Torreglosa, Pavarino-Bertelli Erika Cristina
Abstract excerpt
BACKGROUND: To evaluate the influence of GSTM1 and GSTT1 null genotypes in head and neck carcinogenesis. METHODS: The frequencies of GSTM1 and GSTT1 null genotypes were evaluated by multiplex polymerase chain reaction (PCR) in 45 patients with head and neck squamous cell carcinoma and in 45 control group individuals. Both groups were composed of smokers paired by gender, age and race. RESULTS: The GSTT1 null...
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