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Article

Paths to a malaria vaccine illuminated by parasite genomics

22 Jan 2015

Abstract excerpt

More human death and disease is caused by malaria parasites than by all other eukaryotic pathogens combined. As early as the sequencing of the first human genome, malaria parasite genomics was prioritized to fuel the discovery of vaccine candidate antigens. This stimulated increased research on malaria, generating new understanding of the cellular and molecular mechanisms of infection and immunity. This review of...

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PMID: 25620796
DOI: 10.1016/j.tig.2014.12.005

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