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The case for a rational genome-based vaccine against malaria

22 Jan 2015

Abstract excerpt

Historically, vaccines have been designed to mimic the immunity induced by natural exposure to the target pathogen, but this approach has not been effective for any parasitic pathogen of humans or complex pathogens that cause chronic disease in humans, such as Plasmodium. Despite intense efforts by many laboratories around the world on different aspects of Plasmodium spp. molecular and cell biology, epidemiology...

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PMID: 25657640
DOI: 10.3389/fmicb.2014.00741

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