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Article

Adaptation of a diverse simian immunodeficiency virus population to a new host is revealed through a systematic approach to identify amino acid sites under selection.

Molecular biology and evolution - 1 Mar 2007

Vanderford Thomas H, Demma Linda J, Feinberg Mark B, Staprans Silvija I, Logsdon John M

Abstract excerpt

Simian immunodeficiency viruses (SIV) have had considerable success at crossing species barriers; both human immunodeficiency virus (HIV)-1 and HIV-2 have been transmitted on multiple occasions from SIV-infected natural host species. However, the precise evolutionary and ecological mechanisms characterizing a successful cross-species transmission event remain to be elucidated. Here, in addition to expanding and...

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Identifiers

PMID: 17159231
DOI: 10.1093/molbev/msl194
PMCID: PMC7107550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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