Article
Different evolution of simian immunodeficiency virus in a natural host and a new host.
Virology - 20 Jul 1998
Courgnaud V, Saurin W, Villinger F, Sonigo P
Abstract excerpt
To address the mechanisms of host-virus adaptation and pathogenesis of lentiviral infections, we compared the evolution of the same isolate of simian immunodeficiency virus (SIVsmm9) in two different situations: nonpathogenic infection of its natural host, the sooty mangabey, and AIDS-inducing in...
Topics
- Adaptation, Physiological
- Amino Acid Sequence
- Animals
- Base Sequence
- Cercocebus atys
- DNA Primers
- DNA, Viral
- Evolution, Molecular
- Genetic Variation
- Macaca mulatta
- Molecular Sequence Data
- Phylogeny
- Polymerase Chain Reaction
- Selection, Genetic
- Simian Acquired Immunodeficiency Syndrome
- Simian Immunodeficiency Virus
- Species Specificity
- Virulence