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Article

Variants in mannose-binding lectin and tumour necrosis factor alpha affect survival in cystic fibrosis.

Journal of medical genetics - 1 Mar 2007

Buranawuti Kitti, Boyle Michael P, Cheng Suzanne, Steiner Lori L, McDougal Kathryn, Fallin M Daniele, Merlo Christian, Zeitlin Pamela L, Rosenstein Beryl J, Mogayzel Peter J, Wang Xinjing, Cutting Garry R

Abstract excerpt

BACKGROUND: Patients with cystic fibrosis with the same mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene differ widely in survival suggesting other factors have a substantial role in mortality. OBJECTIVE: To determine if the genotype distribution of variants in three putative cystic fibrosis modifier genes (tumour necrosis factor alpha (TNFalpha), transforming growth factor beta1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17158822
DOI: 10.1136/jmg.2006.046318
PMCID: PMC2598033

Genes

MBL2
CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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