Article
The tumor necrosis factor α (-308 A/G) polymorphism is associated with cystic fibrosis in Mexican patients.
PloS one - 1 Jan 2014
Sanchez-Dominguez Celia N, Reyes-Lopez Miguel A, Bustamante Adriana, Cerda-Flores Ricardo M, Villalobos-Torres Maria Del C, Gallardo-Blanco Hugo L, Rojas-Martinez Augusto, Martinez-Rodriguez Herminia G, Barrera-Saldaña Hugo A, Ortiz-Lopez Rocio
Abstract excerpt
UNLABELLED: Environmental and genetic factors may modify or contribute to the phenotypic differences observed in multigenic and monogenic diseases, such as cystic fibrosis (CF). An analysis of modifier genes can be helpful for estimating patient prognosis and directing preventive care. The aim of this study is to determine the association between seven genetic variants of four modifier genes and CF by comparing...
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