Article
CFTR genotype as a predictor of prognosis in cystic fibrosis.
Chest - 1 Nov 2006
McKone Edward F, Goss Christopher H, Aitken Moira L
Abstract excerpt
STUDY RATIONALE: Certain CFTR genotypes are associated with reduced mortality. The accuracy of using CFTR genotype as a predictor of survival and the mechanisms through which CFTR genotype influences survival are unknown. PARTICIPANTS: All patients with cystic fibrosis (CF) enrolled in the US Cystic Fibrosis Foundation national registry between 1993 and 2002. DESIGN: We examined the prognostic value of CFTR...
Topics
- Adolescent
- Adult
- Cohort Studies
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Female
- Genotype
- Humans
- Lung
- Male
- Middle Aged
- Predictive Value of Tests
