Article
Small-subunit rRNA processome proteins are translationally regulated during differentiation of Trypanosoma cruzi.
Eukaryotic cell - 1 Feb 2007
Nardelli Sheila Cristina, Avila Andréa Rodrigues, Freund Aline, Motta Maria Cristina, Manhães Lauro, de Jesus Teresa Cristina Leandro, Schenkman Sergio, Fragoso Stenio Perdigão, Krieger Marco Aurélio, Goldenberg Samuel, Dallagiovanna Bruno
Abstract excerpt
We used differential display to select genes differentially expressed during differentiation of epimastigotes into metacyclic trypomastigotes in the protozoan parasite Trypanosoma cruzi. One of the selected clones had a sequence similar to that of the small-subunit (SSU) processome protein Sof1p, which is involved in rRNA processing. The corresponding T. cruzi protein, TcSof1, displayed a nuclear localization and...
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