Article
A role for Phospholipase D in Drosophila embryonic cellularization.
BMC developmental biology - 7 Dec 2006
LaLonde Mary, Janssens Hilde, Yun Suyong, Crosby Juan, Redina Olga, Olive Virginie, Altshuller Yelena M, Choi Seok-Yong, Du Guangwei, Gergen J Peter, Frohman Michael A
Abstract excerpt
BACKGROUND: Cellularization of the Drosophila embryo is an unusually synchronous form of cytokinesis in which polarized membrane extension proceeds in part through incorporation of new membrane via fusion of apically-translocated Golgi-derived vesicles. RESULTS: We describe here involvement of the signaling enzyme Phospholipase D (Pld) in regulation of this developmental step. Functional analysis using gene...
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