Article
Enhancement of pyruvate production by osmotic-tolerant mutant of Torulopsis glabrata.
Biotechnology and bioengineering - 1 Jul 2007
Liu Liming, Xu Qinglong, Li Yin, Shi Zhongpin, Zhu Yang, Du Guocheng, Chen Jian
Abstract excerpt
Pyruvate production by Torulopsis glabrata was used as a model to study the mechanism of product inhibition and the strategy for enhancing pyruvate production. It was found that the concentration of cell growth and pyruvate deceased with the increase of NaCl and sorbitol concentrations. To enhance the osmotic stress resistance of the strain, an NaCl-tolerant mutant RS23 was screened and selected through a...
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