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Article

Functional characterization of fibronectin-separated valve interstitial cell subpopulations in three-dimensional culture.

The Journal of heart valve disease - 1 Nov 2010

Stephens Elizabeth H, Carroll Joshua L, Post Allison D, Kuo Joyce J, Grande-Allen K Jane

Abstract excerpt

BACKGROUND AND AIM OF THE STUDY: Myxomatous mitral valves (MVs) contain elevated proportions of myofibroblasts, a valve interstitial cell (VIC) subpopulation that may be important in disease pathogenesis. A novel technique was recently developed for the isolation of VIC myofibroblasts using time-...

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Identifiers

PMID: 21214101
PMCID: PMC4664047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21214101-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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