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Human Cytomegalovirus Latency: Approaching the Gordian Knot

8 Aug 2016

Abstract excerpt

Herpesviruses have evolved exquisite virus-host interactions that co-opt or evade a number of host pathways to enable the viruses to persist. Persistence of human cytomegalovirus (CMV), the prototypical betaherpesvirus, is particularly complex in the host organism. Depending on host physiology and the cell types infected, CMV persistence comprises latent, chronic, and productive states that may occur...

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PMID: 27501258
DOI: 10.1146/annurev-virology-110615-042422

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