Article
Cytomegalovirus infection enhances the immune response to influenza.
Science translational medicine - 1 Apr 2015
Furman David, Jojic Vladimir, Sharma Shalini, Shen-Orr Shai S, Angel Cesar J L, Onengut-Gumuscu Suna, Kidd Brian A, Maecker Holden T, Concannon Patrick, Dekker Cornelia L, Thomas Paul G, Davis Mark M
Abstract excerpt
Cytomegalovirus (CMV) is a β-herpesvirus present in a latent form in most people worldwide. In immunosuppressed individuals, CMV can reactivate and cause serious clinical complications, but the effect of the latent state on healthy people remains elusive. We undertook a systems approach to understand the differences between seropositive and negative subjects and measured hundreds of immune system components from...
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