Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunogenicity of Eight Dormancy Regulon-Encoded Proteins of Mycobacterium tuberculosis in DNA-Vaccinated and Tuberculosis-Infected Mice

4 Dec 2006

Abstract excerpt

Hypoxia and low concentrations of nitric oxide have been reported to upregulate in vitro gene expression of 48 proteins of the dormancy (DosR) regulon of Mycobacterium tuberculosis. These proteins are thought to be essential for the survival of bacteria during persistence in vivo and are targeted by the immune system during latent infection in humans. Here we have analyzed the immunogenicity of eight DosR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Pneumonia and Respiratory Infections
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17145953
DOI: 10.1128/iai.01137-06

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunogenicity of Eight Dormancy Regulon-Encoded Proteins of Mycobacterium tuberculosis in DNA-Vaccinated and Tuberculosis-Infected MicePMID 17145953Read ↗

Immunogenicity of dormancy-related antigens in individuals infected with <i>Mycobacterium tuberculosis</i> in JapanSemantic proximity Read ↗

Lack of Immune Responses to Mycobacterium tuberculosis DosR Regulon Proteins following Mycobacterium bovis BCG VaccinationSemantic proximity Read ↗

Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosisSemantic proximity Read ↗

Immunogenicity of 60 novel latency-related antigens of Mycobacterium tuberculosisSemantic proximity Read ↗

The Mycobacterium DosR regulon structure and diversity revealed by comparative genomic analysis.Semantic proximity Read ↗

Mycobacterium bovis BCG vaccine strains lack narK2 and narX induction and exhibit altered phenotypes during dormancy.Semantic proximity Read ↗

Whole genome identification of Mycobacterium tuberculosisvaccine candidates by comprehensive data mining and bioinformatic analysesSemantic proximity Read ↗

Bioinformatic and Empirical Analysis of Novel Hypoxia-Inducible Targets of the Human Antituberculosis T Cell ResponseSemantic proximity Read ↗

Gene Regulatory Mechanism of Mycobacterium Tuberculosis during DormancySemantic proximity Read ↗

Mycobacterium tuberculosis DosR Regulon Gene Rv2004c Encodes a Novel Antigen with Pro-inflammatory Functions and Potential Diagnostic Application for Detection of Latent TuberculosisSemantic proximity Read ↗

DosR antigen Rv1737c induces activation of macrophages dependent on the TLR2 pathwaySemantic proximity Read ↗

Immune Responses to the Enduring Hypoxic Response Antigen Rv0188 Are Preferentially Detected in Mycobacterium bovis Infected Cattle with Low PathologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.