Article
The relationship between Helicobacter pylori infection and promoter polymorphism of the Nrf2 gene in chronic gastritis
1 Jan 2007
Abstract excerpt
The transcription factor Nrf2 regulates the expression of detoxifying and antioxidant genes. Three polymorphisms of the Nrf2 gene have been reported. We attempted to clarify the relationship between Nrf2 gene polymorphism and chronic gastritis in a Japanese population. The study was performed in 159 patients with no evidence of gastric malignancy on upper gastrointestinal endoscopy (mean age, 62.03 years;...
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