Article
GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population.
World journal of gastroenterology - 1 May 2004
Colombo Jucimara, Rossit Andréa Regina Baptista, Caetano Alaor, Borim Aldenis Albaneze, Wornrath Durval, Silva Ana Elizabete
Abstract excerpt
AIM: To test the hypothesis that, in the Southeastern Brazilian population, the GSTT1, GSTM1 and CYP2E1 polymorphisms and putative risk factors are associated with an increased risk for gastric cancer. METHODS: We conducted a study on 100 cases of gastric cancer (GC), 100 cases of chronic gastritis (CG), and 150 controls (C). Deletion of the GSTT1 and GSTM1 genes was assessed by multiplex PCR. CYP2E1/PstI...
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