Qualitative effects of dioxin on molars vary among inbred mouse strains.

doi:10.1016/j.archoralbio.2006.10.017

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Article

Qualitative effects of dioxin on molars vary among inbred mouse strains.

Archives of oral biology - 1 May 2007

Keller J M, Huet-Hudson Y M, Leamy L J

Abstract excerpt

OBJECTIVE: We evaluated the effects of different levels of the potent environmental toxicant and teratogen, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), on molar development in mice in six inbred strains, all with TCDD responsive Ahr alleles. DESIGN: Pregnant females were exposed on gestation day 13 to 4 different levels of TCDD (control, 0.01, 0.1 and 1.0 microg/kg) and their offspring were examined for the...

Topics

Alleles
Animals
Anodontia
Basic Helix-Loop-Helix Transcription Factors
Environmental Exposure
Environmental Pollutants
Female
Gestational Age
Male
Mice
Mice, Inbred A
Mice, Inbred BALB C
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Inbred CBA

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Identifiers

PMID: 17141729
DOI: 10.1016/j.archoralbio.2006.10.017
PMCID: PMC1916485

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Mice, Inbred Strains

Molar

Molar, Third