Article
Deriving phenotypes for molecular genetic studies of substance use disorders: a family study approach.
Drug and alcohol dependence - 11 May 2007
Faraone Stephen V, Adamson Joel J, Wilens Timothy E, Monuteaux Michael C, Biederman Joseph
Abstract excerpt
Although, family, twin, and adoption studies indicate that genes play a significant etiologic role in the development of substance use disorders (SUDs), the specific genes involved have been difficult to detect due, in part, to uncertainties about how best to define SUDs, the possibility of genetic heterogeneity and the variable phenotypic expression of SUD genotypes. The goal of the present work was to determine...
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