Article
Increasing sequence correlation limits the efficiency of recombination in a multisite evolution model.
Molecular biology and evolution - 1 Feb 2007
Gheorghiu-Svirschevski S, Rouzine I M, Coffin J M
Abstract excerpt
The accumulation of preexisting beneficial alleles in a haploid population, under selection and infrequent recombination, and in the absence of new mutation events is studied numerically by means of detailed Monte Carlo simulations. On the one hand, we confirm our previous work, in that the accumulation rate follows modified single-site kinetics, with a timescale set by an effective selection coefficient s(eff)...
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