Article
Multiple system atrophy in a patient with the spinocerebellar ataxia 3 gene mutation.
Movement disorders : official journal of the Movement Disorder Society - 15 Jan 2007
Nirenberg Melissa J, Libien Jenny, Vonsattel Jean-Paul, Fahn Stanley
Abstract excerpt
The cerebellar variant of multiple system atrophy (MSA-C) has overlapping clinical features with the hereditary spinocerebellar ataxias (SCAs), but can usually be distinguished on a clinical basis. We describe a patient who developed a sporadic, late-onset, rapidly progressive neurodegenerative disorder consistent with MSA-C. Genetic testing, however, showed an abnormal expansion of one allele of the...
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