Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enzymatic Methods for Mutation Detection in Cancer Samples and Liquid Biopsies.

International journal of molecular sciences - 4 Jan 2023

Darbeheshti Farzaneh, Makrigiorgos G Mike

Abstract excerpt

Low-level tumor somatic DNA mutations in tissue and liquid biopsies obtained from cancer patients can have profound implications for development of metastasis, prognosis, choice of treatment, follow-up, or early cancer detection. Unless detected, such low-frequency DNA alterations can misinform patient management decisions or become missed opportunities for personalized medicine. Next-generation sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to DNA, Neoplasm
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liquid Biopsy

Share to Mutation

Share to Neoplasms

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 36674433
DOI: 10.3390/ijms24020923
PMCID: PMC9865676

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enzymatic Methods for Mutation Detection in Cancer Samples and Liquid Biopsies.PMID 36674433Read ↗

Single-copy detection of somatic variants from solid and liquid biopsy.Semantic proximity Read ↗

Incidental pathogenic germline alterations detected through liquid biopsy in patients with solid tumors: prevalence, clinical utility and implications.Semantic proximity Read ↗

Extending Circulating Tumor DNA Analysis to Ultralow Abundance Mutations: Techniques and Challenges.Semantic proximity Read ↗

Clinical mutation assay of tumors: new developments.Semantic proximity Read ↗

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.Semantic proximity Read ↗

Update on the types and usage of liquid biopsies in the clinical setting: a systematic review.Semantic proximity Read ↗

Current and emerging techniques for diagnostic mutation detection: an overview of methods for mutation detection.Semantic proximity Read ↗

Molecular methods for the diagnosis of cancer.Semantic proximity Read ↗

Digital quantification of mutant DNA in cancer patients.Semantic proximity Read ↗

Power and Promise of Next-Generation Sequencing in Liquid Biopsies and Cancer Control.Semantic proximity Read ↗

Liquid Biopsies in the Screening of Oncogenic Mutations in NSCLC and its Application in Targeted Therapy.Semantic proximity Read ↗

Recent Developments in Mutation Enrichment and Detection Technologies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.