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A genome-wide linkage scan for genes controlling variation in renal function estimated by serum cystatin C levels in extended families with type 2 diabetes.

Diabetes - 1 Dec 2006

Placha Grzegorz, Poznik G David, Dunn Jonathon, Smiles Adam, Krolewski Bozena, Glew Timothy, Puppala Sobha, Schneider Jennifer, Rogus John J, Rich Stephen S, Duggirala Ravindranath, Warram James H, Krolewski Andrzej S

Abstract excerpt

We performed a variance components linkage analysis of renal function, measured as glomerular filtration rate (GFR), in 63 extended families with multiple members with type 2 diabetes. GFR was estimated from serum concentrations of cystatin C and creatinine in 406 diabetic and 428 nondiabetic relatives. Results for cystatin C were summarized because they are superior to creatinine results. GFR aggregates in...

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PMID: 17130480
DOI: 10.2337/db06-0781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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