Article
Copper supplementation increases yeast life span under conditions requiring respiratory metabolism.
Mechanisms of ageing and development - 1 Feb 2007
Kirchman Paul A, Botta Gabriela
Abstract excerpt
To further exploit yeast as a model for cellular aging we have modified the replicative life span assay to force respiration, by replacing glucose with the non-fermentable carbon source glycerol. The growth rates of several different strains varied greatly, with doubling times ranging from 2.7 to 7 h. Life spans of all strains were lower on media containing glycerol than on media containing glucose. However,...
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