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Article

Reduction of hypertrophic scar via retroviral delivery of a dominant negative TGF-beta receptor II.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS - 1 Jan 2007

Reid Russell R, Roy Nakshatra, Mogford Jon E, Zimmerman Hannah, Lee Chung, Mustoe Thomas A

Abstract excerpt

Effective blockade of the pluripotent cytokine transforming growth factor (TGF)-beta as a means of cutaneous scar reduction is a strategy with great potential. This desired effect may be achieved through the overexpression of mutant TGF-beta receptors within the wound milieu. Our goal was to examine the effects of dominant negative mutant TGF-beta receptor II (TGFbetaRIIdn) protein expression in a...

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Identifiers

PMID: 17126268
DOI: 10.1016/j.bjps.2005.12.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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