Article
Interactions between GSTM1, GSTT1 and GSTP1 polymorphisms and smoking and intake of fruit and vegetables in relation to lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Feb 2007
Sørensen Mette, Raaschou-Nielsen Ole, Brasch-Andersen Charlotte, Tjønneland Anne, Overvad Kim, Autrup Herman
Abstract excerpt
Polymorphisms in glutathione S-transferases (GST) are weakly associated with risk for lung cancer. We examined gene-environment interactions in relation to lung cancer in 430 cases and 767 comparison persons identified within a prospective cohort of 57,053 persons. We used assays capable of discriminating heterozygous individuals from those with two functional alleles and homozygous deletions in GSTM1 and GSTT1....
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