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Article

SNPs and interaction analyses of noelin 2, myocilin, and optineurin genes in Japanese patients with open-angle glaucoma.

Investigative ophthalmology & visual science - 1 Dec 2006

Funayama Tomoyo, Mashima Yukihiko, Ohtake Yuichiro, Ishikawa Karin, Fuse Nobuo, Yasuda Noriko, Fukuchi Takeo, Murakami Akira, Hotta Yoshihiro, Shimada Naoki

Abstract excerpt

PURPOSE: To evaluate the noelin 2 gene as a disease-causing factor for open-angle glaucoma (OAG) and the interactions between the noelin 2 (OLFM2), optineurin (OPTN), and myocilin (MYOC) genes. METHODS: OLFM2 was analyzed in 770 Japanese subjects including 215 patients with elevated intraocular pressure (IOP), 277 with normal IOP, 38 with juvenile open-angle glaucoma, and 240 control subjects. Two...

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Source

Identifiers

PMID: 17122126
DOI: 10.1167/iovs.06-0196

Genes

OLFM2
OPTN
MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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