Article
Influence of endothelial nitric oxide synthase T-786C single nucleotide polymorphism on aneurysm size.
Journal of neurosurgery - 1 Jan 2005
Akagawa Hiroyuki, Kasuya Hidetoshi, Onda Hideaki, Yoneyama Taku, Sasahara Atsushi, Kim Chul-Jin, Lee Jung-Chung, Yang Tae-Ki, Hori Tomokatsu, Inoue Ituro
Abstract excerpt
OBJECT: Among patients with aneurysms, those with heterozygous (T/C) endothelial nitric oxide synthase (eNOS) T-786C single nucleotide polymorphism (SNP), a mutation reducing endothelial nitric oxide synthesis, are reported to have larger ruptured intracranial aneurysms (IAs) than those with homozygous (C/C or T/T) genotype. The authors tested patients harboring aneurysms for eNOS T-786C SNP in two...
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