Article
Study of a functional polymorphism in the p53 gene in systemic lupus erythematosus: lack of replication in a Spanish population.
Lupus - 1 Jan 2006
Sánchez E, Sabio J M, Callejas J L, de Ramón E, de Haro M, Jiménez-Alonso J, Ortego-Centeno N, Sánchez-Román J, González-Gay M A, López-Nevot M A, González-Escribano M F, Martín J
Abstract excerpt
The aim of this study was to assess the possible association between the p53 suppressor gene codon 72 polymorphism and systemic lupus erythematosus (SLE). Our study population consisted of 513 SLE patients and 567 healthy controls. All the individuals were of Spanish Caucasian origin. Genotyping of the p53 codon 72 polymorphism was performed by allele-specific PCR. No statistically significant differences were...
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