Article
Polymorphism at codon 72 of the p53 gene is not associated with endometriosis in a Japanese population.
Journal of the Society for Gynecologic Investigation - 1 May 2004
Omori Shinya, Yoshida Shigeki, Kennedy Stephen H, Negoro Kenichi, Hamana Shinya, Barlow David H, Maruo Takeshi
Abstract excerpt
OBJECTIVE: Endometriosis is inherited as a complex trait, which means that multiple susceptibility genes interact with each other and the environment to produce the phenotype. Previous studies have implicated p53, a tumor suppressor gene, as a factor in the development of the disease. In a Japanese population, we investigated the frequency of the p53 polymorphism in women affected with endometriosis. METHODS: We...
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