Article
Establishment and characterization of a human cell line derived from a uterine papillary serous carcinoma with wild-type p53 function.
Human cell - 1 Aug 2008
Hashimoto Hisashi, Kojima Atsumi, Sudo Tamotsu, Ohki Noriyoshi, Yamaguchi Satoshi, Mikami Yoshiki, Ito Masaharu, Nishimura Ryuichiro
Abstract excerpt
Uterine papillary serous carcinoma is an uncommon histologic subtype of endometrial cancer that behaves aggressively and has a poor prognosis. We successfully established a uterine papillary serous carcinoma cell line. The population-doubling time was approximately 16 h. Although loss of p53 function is considered critical for the molecular pathogenesis of uterine papillary serous carcinoma, p53 was not only...
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