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The Up-Regulation of TP53 Impairs Decidualization by Promoting Apoptosis of Decidual Stromal Cells in Unexplained Recurrent Spontaneous Abortion

2022-08-31

Abstract excerpt

<h4>Objectives: </h4> This study aims to clarify the regulation mechanism of TP53 in the impaired decidualization of unexplained recurrent spontaneous abortion (URSA). <h4>Methods:</h4> RNA-seq analysis was conducted on decidual stromal cells (DSCs) from patients with URSA and healthy controls. TP53 overexpression lentivirus and TP53 shRNA lentivirus were respectively transfected into the human endometrial stromal...

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Literature Corpus work
253b917c-9d33-528d-ab11-21fb0aec2787
DOI
10.21203/rs.3.rs-2006519/v1
Open publication

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The Up-Regulation of TP53 Impairs Decidualization by Promoting Apoptosis of Decidual Stromal Cells in Unexplained Recurrent Spontaneous AbortionDOI 10.21203/rs.3.rs-2006519/v1
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