Article
The subcellular localisation of trypanosome RRP6 and its association with the exosome.
Molecular and biochemical parasitology - 1 Jan 2007
Haile Simon, Cristodero Marina, Clayton Christine, Estévez Antonio M
Abstract excerpt
The exosome, a complex of 3'-exoribonucleases and associated proteins, is involved in the degradation of eukaryotic mRNAs in the cytoplasm, and has RNA processing and quality control functions in the nucleus. In yeast, the nuclear exosome differs from the cytoplasmic one in that it contains an additional non-essential component, Rrp6p. In contrast, a small proportion of human RRP6 has been shown to localise to...
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